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RB Rankings: Week 15
| Rank | Name | Team | Position | Opponent |
|---|---|---|---|---|
| 1 | Saquon Barkley | PHI | RB | vs PIT |
| 2 | Bijan Robinson | ATL | RB | @ LV |
| 3 | Derrick Henry | BAL | RB | @ NYG |
| 4 | Joe Mixon | HOU | RB | vs MIA |
| 5 | De’Von Achane | MIA | RB | @ HOU |
| 6 | Chase Brown | CIN | RB | @ TEN |
| 7 | Josh Jacobs | GB | RB | @ SEA |
| 8 | Jahmyr Gibbs | DET | RB | vs BUF |
| 9 | Kyren Williams | LAR | RB | @ SF |
| 10 | James Conner | ARI | RB | vs NE |
| 11 | Breece Hall | NYJ | RB | @ JAC |
| 12 | Alvin Kamara | NO | RB | vs WAS |
| 13 | Tony Pollard | TEN | RB | vs CIN |
| 14 | Chuba Hubbard | CAR | RB | vs DAL |
| 15 | Brian Robinson Jr. | WAS | RB | @ NO |
| 16 | Jonathan Taylor | IND | RB | @ DEN |
| 17 | Aaron Jones Sr. | MIN | RB | vs CHI |
| 18 | Rico Dowdle | DAL | RB | @ CAR |
| 19 | James Cook | BUF | RB | @ DET |
| 20 | David Montgomery | DET | RB | vs BUF |
| 21 | Kenneth Walker III | SEA | RB | vs GB |
| 22 | Rachaad White | TB | RB | @ LAC |
| 23 | Najee Harris | PIT | RB | @ PHI |
| 24 | Rhamondre Stevenson | NE | RB | @ ARI |
| 25 | Isiah Pacheco | KC | RB | @ CLE |
| 26 | Tyrone Tracy Jr. | NYG | RB | vs BAL |
| 27 | D’Andre Swift | CHI | RB | @ MIN |
| 28 | Braelon Allen | NYJ | RB | @ JAC |
| 29 | Bucky Irving | TB | RB | @ LAC |
| 30 | Sincere McCormick | LV | RB | vs ATL |
| 31 | Patrick Taylor Jr. | SF | RB | vs LAR |
| 32 | Travis Etienne Jr. | JAC | RB | vs NYJ |
| 33 | Zach Charbonnet | SEA | RB | vs GB |
| 34 | Jaylen Warren | PIT | RB | @ PHI |
| 35 | Tank Bigsby | JAC | RB | vs NYJ |
| 36 | Nick Chubb | CLE | RB | vs KC |
| 37 | Gus Edwards | LAC | RB | vs TB |
| 38 | Javonte Williams | DEN | RB | vs IND |
| 39 | Justice Hill | BAL | RB | @ NYG |
| 40 | Jaleel McLaughlin | DEN | RB | vs IND |
| 41 | Kareem Hunt | KC | RB | @ CLE |
| 42 | Jerome Ford | CLE | RB | vs KC |
| 43 | Isaiah Davis | NYJ | RB | @ JAC |
| 44 | Tyjae Spears | TEN | RB | vs CIN |
| 45 | Kimani Vidal | LAC | RB | vs TB |
| 46 | Ameer Abdullah | LV | RB | vs ATL |
| 47 | Tyler Allgeier | ATL | RB | @ LV |
| 48 | Cam Akers | MIN | RB | vs CHI |
| 49 | Jeremy McNichols | WAS | RB | @ NO |
| 50 | Devin Singletary | NYG | RB | vs BAL |
| 51 | Ray Davis | BUF | RB | @ DET |
| 52 | Kendre Miller | NO | RB | vs WAS |
| 53 | Antonio Gibson | NE | RB | @ ARI |
| 54 | Kenneth Gainwell | PHI | RB | vs PIT |
| 55 | Audric Estime | DEN | RB | vs IND |
| 56 | Jaylen Wright | MIA | RB | @ HOU |
| 57 | Ke’Shawn Vaughn | SF | RB | vs LAR |
| 58 | Blake Corum | LAR | RB | @ SF |
| 59 | Trey Benson | ARI | RB | vs NE |
| 60 | Sean Tucker | TB | RB | @ LAC |
| 61 | Ty Johnson | BUF | RB | @ DET |
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