With Tyreek Hill sidelined, Jaylen Waddle steps into the WR1 role. The last time he was the featured option, he averaged nearly 9 targets per game. He should lead the Dolphins in targets against the Panthers. The matchup isn’t overly favorable for wide receivers, but Waddle’s volume and role make him a reliable WR2 play in Week 5. –Steve Pintado
Darius Slayton also gets a boost with Malik Nabers out. In two games without Nabers last season, he saw 22 targets, 179 yards, and 1 TD. This week, he faces the Saints, who rank in the bottom 10 in fantasy points allowed to WRs. That sets him up as a sneaky FLEX option with WR3 upside if the Giants lean on him again. –Steve Pintado
Chris Olave has been a target machine (43 on the season) and now draws the second-best matchup for WRs against the Giants. Just last week, we saw Quentin Johnston finish as a top-5 fantasy WR against this same defense. With volume plus matchup aligning, Olave profiles as a strong WR2 with WR1 upside in Week 5. Rashid Shaheed moves into the FLEX conversation during bye weeks. The Giants’ secondary has been a liability, and his big-play ability makes him a high-variance but appealing option. In deeper leagues or if you’re short on starters, he’s a boom-or-bust FLEX in Week 5. –Steve Pintado
It might be tempting to roll Jerry Jeudy out with Cedric Tillman on IR, but this is a spot to fade him. Rookie QB Dillon Gabriel makes his first start — on the road in London — against a Vikings defense that’s been stingy. Minnesota ranks 1st in fantasy points allowed to WRs and comes into this matchup well-prepared after adjusting to the time zone. With shaky QB play and a tough defensive matchup, Jeudy is best left on benches in Week 5. Let’s not forget that the Vikings have been hanging out in Europe after playing in Dublin last week. –Steve Pintado