Sit/Start Week 10 Reviewing All Fantasy Relevant Players In Every Single Game

Our team tells you who you should be starting in week 10 of the fantasy football season

Game Info


Kickoff: Sunday, November 15th, at 4:25 PM EST

Location: Mercedes-Benz Superdome, New Orleans, Louisiana

Betting Odds: SF +9, 50 total via Oddsshark

Network: FOX


San Francisco 49ers



Nick Mullens (Sit)


Handed the starting job due to the latest Jimmy Garopollo injury, Nick Mullens has been middling in relief. Last Thursday against the Packers, most of his production came in garbage time, which is fine from a fantasy standpoint. However, he’s not a viable streamer even though the Saints defense is allowing three touchdowns per game to the quarterback position this season.


Running Backs

Jerick McKinnon (Start, RB2), JaMycal Hasty (Sit)


Jerick McKinnon had his fantasy night saved against Green Bay as he scored on a one-yard rush with just four seconds left in the game. That said, as one of two healthy 49ers running backs right now, McKinnon finds himself as an RB2 in an offense that is lacking playmakers due to injury. Tevin Coleman is still expected to miss time, and Raheem Mostert in all reality will be held out through next week’s BYE. Many were hopeful their grab of JaMycal Hasty off the wire a week or so ago would pay off, but it certainly has not. Against the Packers, he had just three yards on four carries, and two receptions for 10 yards.


Wide Receivers/Tight End

Brandon Aiyuk (Start, WR3), Deebo Samuel (Sit), Kendrick Bourne (Sit), Richie James (Sit), Ross Dwelley (Start if you must, TE2), Jordan Reed (Sit)


Threes a crowd as far as returnees for San Fran. Brandon AiyukDeebo Samuel, and Kendrick Bourne were activated off the COVID-19 list this week after missing last Thursday’s game. Out of the trio, Aiyuk for sure gets the starting nod in your lineup. Samuel could return, but also could be held out and/or limited if active, given the fact that Week 11 is the 49ers BYE. Bourne is a sit, and the same goes for Richie James, despite his explosion last week; which only came as he was the lone healthy receiver on the field. Aiyuk and co. will face off against a New Orleans defense that has given up the 15th most fantasy points to wide receivers this season.

Tight end Ross Dwelley could be in line for a bigger game this week as the Saints defense has given up the seventh-most fantasy points to his position on the year. He caught all three of his targets last week for 52 yards. Jordan Reed, on the other hand, was a dud against Green Bay in his return to action, as he was only targeted twice in the blowout. It’s hard to trust Reed, and I would only consider starting Dwelley if you’re desperate.


New Orleans Saints



Drew Brees (Start, QB1)


In last week’s unexpected blowout of Tampa Bay, Drew Brees carved up the Bucs for 222 yards and four touchdowns. He’s had a hot hand for the last three weeks, targeting and completing to anyone open… and I mean anyone. With his WR1 back in the fold, the QB1 production should continue against a depleted 9ers defense that has given up 11t-most passing touchdowns this season with 16.


Running Backs

Alvin Kamara (Start, RB1), Latavius Murray (Sit)


Need I go into detail on Alvin Kamara? He’s a locked-in RB1, and if fantasy owners had any complaints, it’s that they want to see him find the end zone more. Last week against the Buccaneers was actually a down game for Kamara despite scoring, as he only rushed for 40 yards on nine carries and caught five of six targets for nine yards. His box score was halted given the fact that he was rested most of the second half. Latavius Murray remains an important handcuff to roster.


Wide Receivers/Tight End

Michael Thomas (Start, WR1), Emmanuel Sanders (Start, WR3), Jared Cook (Start, TE2)


Welcome back MT. Michael Thomas looked over his nagging injuries, though he had a quiet night in his return. He reeled in five catches on six targets for 51 yards against Tampa Bay. Look for him to be involved more against San Francisco even though they have given up the 15th fewest fantasy points to the wide receiver position on the year. Emmanuel Sanders was a beneficiary of one of Brees’ four touchdowns last week and is cemented as the New Orleans WR2. Even with Thomas back, you could do worse than Sanders most weeks as your WR3/FLEX option.

Jared Cook had only three targets last week, in which he caught two with a fumble in an attempt to score. His involvement could fade a bit with Thomas back in the fold, but like Sanders, you could do worse than Cook in the barren TE landscape.

Matthew Cava (@cavaM_ Twitter & Reddit)

5 responses to “Sit/Start Week 10 Reviewing All Fantasy Relevant Players In Every Single Game”

  1. Gene says:

    I am starting Jones/Chubb at RB and Thomas, Chark and Cooks at WR. Who then would you recommend at Flex out of the following: Hunt, Edmonds, Justin Jefferson or DJ Moore? Maybe Hunt should start over Chubb this week? (12 team ppr league) It’s an embarrassment of riches to be sure and results in a bit of a paralysis by analysis.

  2. Steve says:

    RB’s – Henderson, Edmonds, Taylor & Drake. Which 2 would you start? would you consider starting both Edmonds & drake (if he’s healthy)? Thanks. Great article. Look forward to it every week.


  3. Edgar says:

    Podcast host: Do you think that [insert hot take here]
    Other guy: Nah…
    Podcast host: Yeah, I agree

  4. Jay says:

    Tough choice, which two: Allen, Brown, Fuller?

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