Game Info
Kickoff: Sunday, October 25, 2026, 1:00 PM ET
Location: U.S. Bank Stadium, Minneapolis, MN
Network: CBS
Indianapolis Colts
Quarterback
Daniel Jones: SIT
Daniel Jones walks into Minnesota on Sunday carrying a 59.6% completion rate and a 4:6 touchdown-to-interception ratio. The defense waiting for him has allowed the lowest completion percentage in football (53.2%) and the fewest fantasy points to quarterbacks per game. The Vikings have twice as many interceptions (six) and passing touchdowns allowed (three) in five games and are coming off a bye. So long, partner.
Running Back
Jonathan Taylor: START, RB1
Jonathan Taylor is staying in your lineup every single week. He’s basically Apple Health. You ignore it for a bit, open it back up, and it’s already at 10,000 steps and 100 yards.
Wide Receiver
Keenan Allen: START, WR3
Josh Downs: FLEX, WR4
Laquon Treadwell: SIT
Considering the matchup and the play of Jones, I’d rather not start Keenan Allen or Josh Downs if possible. Allen gets the slight edge because he’s averaging almost 10 targets per game in his last three and scored over 15 fantasy points in two of them. Downs had a two-game stretch with about 13 points a game, but hasn’t surpassed 10 since Week 3. Minnesota is one of the worst matchups for wide receivers, and you should look elsewhere if you can.
Tight End
Tyler Warren: START (If Active)
Tyler Warren wasn’t practicing at the time of writing, and his status for Sunday is unclear. If he’s able to play, he’s still a start even with the worst matchup for tight ends on deck. Warren is the TE6 on the season and averaging seven catches per game in his last three.
Defense/Special Teams
Indianapolis Colts: SIT
Indy is tied for the fewest takeaways in the league and allows the sixth-most points per game.
Minnesota Vikings
Quarterback
Kyler Murray: START (in Superflex), Borderline QB1
Kyler Murray had his best game of the season against the Saints in Week 5 and hopes to keep it going against a Colts defense that has just two interceptions on the season. He’s not done much to impress, but to be fair, Murray has yet to complete a pass in a Vikings uniform with both Justin Jefferson and Jordan Addison healthy and on the field. He’s thrown to a healthy Jefferson/Addison combo for about 11 minutes of game clock all year: the first eight minutes of Week 1 and the first four of Week 3. It’s a solid matchup, and if Murray can get both of his top receivers on the field together for a full game, we could see the upside of this offense come to fruition.
Running Back
Aaron Jones Sr: START, RB2
Jordan Mason: SIT
Demond Claiborne: SIT
Jordan Mason is set to return from his thumb injury that cost him Weeks 2-6, but as much as I wish I could, there is no denying Aaron Jones has thrived as the Vikings’ bell cow in his absence. Mason is extremely talented but has to prove he can provide consistency and also stay on the field. The Colts are a great fantasy matchup for running backs and are allowing 45.2 receiving yards to the position. I don’t expect Mason to step right in and take away significant work, which is why I have him as a sit this week. But I do think he takes just enough to prevent Jones from being an RB1.
Wide Receiver
Justin Jefferson: START, WR1
Jordan Addison: START, WR3
Justin Jefferson is a must-start, period. He’s your Photos app. The catch already looks ridiculous, then you press and hold for the Live Photo and realize the still frame somehow undersold it. Jordan Addison missed Week 6 with a hamstring injury but returned to full practice and is expected to suit up Sunday. Addison has just one game over 10 fantasy points, but is averaging about seven targets per game in his last three played and an aDOT of 12.4. The Colts allow the fifth-highest yards per route run and ninth-most total yards per game. Were it not for byes, Addison would be more of a FLEX play. But with four teams not playing, he’s bumped to a low-end WR3.
Tight End
T.J. Hockenson: SIT
T.J. Hockenson is coming back from a concussion with one touchdown and two games over 10 points all season. There’s no reason to rush him back into your lineup.
Defense/Special Teams
Minnesota Vikings: START
Minnesota is the best defense in the league, and it’s not close.