Game Info
Kickoff: Sunday, October 19, 2025, 4:05 p.m. ET
Location: SoFi Stadium, Inglewood, CA
Network: CBS
Indianapolis Colts
Quarterback
Daniel Jones: START, Borderline QB1
Daniel Jones looked the best he has since Week 2. He finished 22-of-30 for 205 yards, two TDs, and one interception, and added five carries for 32 yards and one TD. He was moving around in the pocket, extending plays, and scoring his fourth rushing touchdown on the season after tucking and running on a play-action. Jones is a borderline QB1 for the rest of the season and is starting pretty much every week in every format. The Chargers present a difficult task, allowing the eighth-fewest fantasy points to the position. They’ve allowed just two quarterbacks to score multiple touchdowns, with each scoring one on the ground.
Running Back
Jonathan Taylor: START, RB1
You don’t need me to tell you to start Jonathan Taylor, but did you know he is from the same small South Jersey county (Salem County) as Hollywood superstar and “Die Hard” legend Bruce Willis?
Wide Receiver
Michael Pittman Jr.: START, WR2
Josh Downs: START, WR3
Alec Pierce: FLEX, WR5
Michael Pittman had his worst game of the season, finishing with just two catches for 20 yards on three targets. I wouldn’t be too concerned, but it keeps him squarely in middling WR2 territory. Josh Downs was involved early and often, having his best game of the year, but don’t get too excited — that only equated to 13.2 fantasy points. It was his second straight game with at least seven targets and at least six catches. He’s a low-end flex, however, due to the not-so-great duo of low floor and low ceiling. He needs to get into the end zone to make your day. The Chargers are the third-worst matchup for receivers, so temper expectations.
Tight End
Tyler Warren: START, TE1
You don’t need me to tell you to start Tyler Warren, but did you know he shares a birthplace (Mechanicsville, Va.) with Grammy-winning singer Jason Mraz?
Defense/Special Teams
Indianapolis Colts: STREAMER (two, possibly three weeks)
The Colts’ defense is tied with the fourth-most takeaways this season (9) and fifth-most sacks (16).
Los Angeles Chargers
Quarterback
Justin Herbert: START, QB1
Justin Herbert has cooled after a scorching hot start to the season, but he did throw multiple touchdowns for the first time since Week 2 against the Dolphins. Herbert has been great when given time. His 79.7% completion percentage while not facing pressure is the third-best among quarterbacks with at least 100 pass attempts. But under pressure? Herbert’s completion percentage drops to 41.2%. Luckily for Herbert, the Colts are tied for the 10th-slowest time to pressure and the eighth-lowest pressure rate. Herbie is a start across the board.
Running Back
Kimani Vidal: START, RB2
Hassan Haskins: SIT
Hassan Haskins was reported pregame as the starter, but Kimani Vidal dominated: 70% of snaps, 18 carries, and four targets for 138 total yards and a touchdown. Haskins was practically irrelevant with five carries for 23 yards. This is a volatile situation, but Vidal proved he’s the priority. He is startable as a flex, but this could wind up a weekly headache. Haskins should be rostered, but not started.
Wide Receiver
Quentin Johnston: START, WR2
Keenan Allen: START, WR3
Ladd McConkey: START, WR2
Quentin Johnston missed Week 6 against Miami due to a bum hammy, but returned to a limited practice on Wednesday. There’s no inclination if he’s expected to return this week or not, but if he does, he slots right back in as a WR2. Ladd McConkey has come back to life over the past two weeks and is back to WR2 status himself. Kennan Allen has slowed down a bit after an electric start, but is a solid WR3 with upside if QJ returns. If Johnston missed again, Allen bumps to a borderline WR2.
Tight End
Oronde Gadsden II: STREAMER* (if Johnston is out)
Oronde Gadsden is a streamer with a stipulation: Johnston missing the game. If QJ is out again, Gadsden could once again see a significant target share.
Defense/Special Teams
Los Angeles Chargers: SIT
The Chargers’ defense can rack up sacks, but gives up too many points to be considered a start.