Game Info
Kickoff: Sunday, November 9, 2025, 4:05 p.m. ET
Location: Lumen Field, Seattle, WA
Network: CBS
Arizona Cardinals
Quarterback
Kyler Murray*Placed on IR*
Jacoby Brissett: SIT, QB2 (startable in Superflex)
Some say it was a “soft benching.” The Cardinals claim Kyler Murray just needs more time to heal. But with Murray placed on IR, Jacoby “Brisket” Brissett will remain the starting quarterback for Arizona through at least Week 13. Brissett has played much better than Murray, throwing multiple touchdowns in each of his three starts, but faces a tough test heading into Seattle. The Seahawks have allowed just one 300-yard passer and are tied for the fourth-fewest passing touchdowns given up. He’s startable in Superflex, but I’m avoiding him in 1QB leagues.
Running Back
Bam Knight: SIT
Emari Demercado: SIT
If neither Bam Knight nor Emari Demarcado could muster up double-digit fantasy points against the Cowboys, I’m not starting any Cardinals running back until Trey Benson returns from IR. The Cardinals have yet to open up his 21-day practice window, so it sounds like that wont be Week 10.
Wide Receiver
Marvin Harrison Jr.: START, WR2
Zay Jones: SIT
Michael Wilson: SIT
Brissett starting for the Cards for at least the next four games is a boon to the fantasy value of Marvin Harrison Jr., who’s coming off his first 20-point fantasy performance of the season. Marv also scored his second touchdown of the season and had at least 10 targets for the second time. It was nice to see MHJ have a ceiling-esque game, but he’ll have a hard time repeating against a Seattle defense allowing the eighth-fewest points to the position.
Tight End
Trey McBride: START, TE1
There is no debate in starting Trey McBride, but did you know that in 2024, he became the first tight end in NFL history to record 12 or more receptions in back-to-back games?
Defense/Special Teams
Arizona Cardinals: SIT
The Cardinals’ defense isn’t awful, but it isn’t doing enough to warrant consideration in fantasy.
Seattle Seahawks
Quarterback
Sam Darnold: START, QB1
Sam Darnold, MVP candidate? Well, after throwing four touchdowns in a game for the second time this season and Seattle tied for the division lead, he kinda has to be. Regardless, Darnold is certainly in the fantasy MVP running. He’s sporting a 70.4% completion rate, ranks first in yards per attempt (9.65) among quarterbacks with at least 50 pass attempts, inside the top 10 in passing yards, passing touchdowns, and third in passer rating. Darnold faces a stiff test in Arizona, which has allowed multiple passing touchdowns in a game just twice and is giving up the eighth-fewest fantasy points to opposing quarterbacks.
Running Back
Zach Charbonnet: FLEX, RB3
Kenneth Walker III: FLEX, RB3
Kenneth Walker III is averaging nearly 2 more yards per carry than Zach Charbonnet (4.45 to 2.88). Walker has triple the explosive run rate (7.5% to 2.5%), a higher success rate, missed forced tackles per attempts, lower stuffed rate, etc., etc., yet is still stuck sharing the workload nearly 50-50. Both are flex plays while this scam of a committee continues.
Wide Receiver
Jaxon Smith-Njigba: START, WR1
Tory Horton: SIT
Cooper Kupp: SIT
Rashid Shaheed: SIT
Jaxon Smith-Njigba is obviously a lock in your lineup, but did you know that he recently became the first player in Seahawks history to record four consecutive 100-yard receiving games? Cooper Kupp isn’t practicing at the time of writing, but hasn’t done enough to be considered a weekly fantasy starter. The Tony Horton hype train, however, was ready to run right off the rails after his two-touchdown performance on “Sunday Night Football.” But the Seahawks’ acquisition of Rashid Shaheed put the brakes on the Horton express. Both should be rostered, but until we see how things shake out from a target perspective, it’s too big a risk to start either Horton or Shaheed.
Tight End
AJ Barner: SIT
Elijah Arroyo: SIT
Neither Seahawks tight end is consistent enough to be considered a streamer.
Defense/Special Teams
Seattle Seahawks: START
The Seahawks are one of six teams allowing fewer than 20 points per game. They also rank inside the top three in sacks.