Game Info
Kickoff: Sunday, September 20, 2026, 8:25 PM ET
Location: State Farm Stadium, Glendale, AZ
Network: FOX
Seattle Seahawks
Quarterback
Sam Darnold: Out
Drew Lock: SIT
A completion, an incompletion, and then a sack that knocked him out of the game. Out goes Sam Darnold, in comes Drew Lock. Seattle leaned on play action, screens, and short outs, though the screens weren’t going anywhere. Lock and the Seahawks head to Arizona for a division matchup against a Cardinals team that shut down the uber hyped offense of the Chargers and put pressure on Justin Herbert at a 42.9% clip. Lock’s only an option as a desperation play in Superflex leagues.
Running Back
Jadarian Price: FLEX, RB3
George Holani: SIT
Emanuel Wilson: SIT
Jadarian Price only played 50% of snaps, had just two more carries than George Holani, and no work in the red zone or on third downs. Price is a dart-throw FLEX that you’re betting on explosiveness, but you’re gambling with a goose egg. I’m not confident in starting either Holani or Emanuel Wilson in this one.
Wide Receiver/Tight End
Jaxon Smith-Njigba: START, WR1
Rashid Shaheed: SIT
Cooper Kupp: SIT
AJ Barner: SIT
Even with Drew Lock under center, Jaxon Smith-Njigba has cemented himself as a must-start regardless of matchup. He finished Week 1 with 26.2 fantasy points despite Lock playing all but about 30 seconds of the game. However, while Lock is the team’s starter, JSN is the only Seattle pass catcher worth starting.
Defense/Special Teams
Seattle Seahawks: START
Can’t argue with three sacks, three interceptions, and holding the Pats to under 300 total yards of offense.
Arizona Cardinals
Quarterback
Jacoby Brissett: SIT
Jacoby Brissett completed nearly 73% of his passes for 277 yards, with one touchdown and no interceptions. Pretty much what we’ve come to expect from him. If you’re in a bind at quarterback in Superflex, I guess I understand starting him. But with his already limited ceiling, facing Seattle really makes me want to park him on the bench.
Running Back
Jeremiyah Love: FLEX, RB3
Tyler Allgeier: FLEX, RB3
Jeremiyah Love was able to score the first touchdown of his NFL career, but it was Tyler Allgeier who had the heaviest workload, handling 17 rushing attempts and two targets to Love’s 11 and three. The duo split work inside the five. It’s a matter of time before Love overtakes this backfield, but both his ceiling and floor are handicapped as long as Allgeier is getting a somewhat healthy workload. And yes, the Seahawks are still a very tough matchup in the run game. Temper your expectations for the 2026 third overall pick here.
Wide Receiver
Marvin Harrison Jr.: FLEX, WR4
Michael Wilson: FLEX, WR4
Kendrick Bourne: SIT
I’m not overly concerned about Michael Wilson leading receivers with seven targets to Marvin Harrison Jr.‘s three. I am concerned with his seven first-read targets to Marv’s two. Against Seattle’s secondary that gave up just 5.74 yards per target against the Pats, both are middling FLEX plays. I have Marv ranked two spots ahead of Wilson, but I’d understand if you feel more confident in the latter at this point.
Tight End
Trey McBride: START, TE1
Nobody needs to be told to start Trey McBride. He’s the free car vacuum at the gas station: you fully expect a hair dryer and wind up getting a jet engine. Your car has never been this clean. Your tight end spot has never been this good. Even against a top-tier defense, McBride should command a massive target share and produce elite numbers.
Defense/Special Teams
Arizona Cardinals: SIT
I want to see a few more games of solid defensive play before I’m ready to consider starting them.